Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12149663 | 0.87 | FDPS (0.65) | FDPSDHODHMCL1PARP15PARP10 | |
| SCHEMBL12149598 | 0.86 | FDPS (0.60) | FDPSDHODHMCL1PARP15PARP10 | |
| SCHEMBL1375302 | 0.83 | FDPS (0.66) | FDPSMCL1PARP15PARP10MEN1 | |
| SCHEMBL12149587 | 0.82 | FDPS (0.70) | FDPSDHODHMCL1PARP15PARP10 | |
| SCHEMBL12149637 | 0.81 | FDPS (0.63) | FDPSMCL1PARP15PARP10MEN1 | |
| SCHEMBL1377048 | 0.81 | FDPS (0.66) | FDPSMCL1PARP15PARP10MEN1 | |
| SCHEMBL1378315 | 0.81 | FDPS (0.78) | FDPSMCL1PARP15PARP10MEN1 | |
| SCHEMBL12149601 | 0.81 | FDPS (0.68) | FDPSMCL1PARP15PARP10MEN1 | |
| SCHEMBL12149695 | 0.81 | FDPS (0.68) | FDPSMCL1PARP15PARP10MEN1 | |
| SCHEMBL27861648 | 0.80 | FDPS (0.62) | FDPSMCL1PARP15PARP10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043584-A1 | SALICYLIC ACID DERIVATIVES BEING FARNESYL PYROPHOSPHATE SYNTHASE ACTIVITY INHIBITORS | NOVARTIS AG (CH) | 2010-04-22 | — | — | WO | disclosed |