Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.84 |
| ▸ | MEN1 | O00255 | 6/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.84 |
| ▸ | MAPT | P10636 | 5/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.84 |
| ▸ | LMNA | P02545 | 4/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | EEF2K | O00418 | 9/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186407 | 0.91 | ALDH1A1 (0.86) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14969506 | 0.90 | ALDH1A1 (0.97) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL13186408 | 0.90 | KMT2A (0.86) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL18537648 | 0.90 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL14969396 | 0.89 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL426340 | 0.87 | MEN1 (0.80) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL18819112 | 0.86 | KMT2A (0.81) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL427662 | 0.86 | MEN1 (0.80) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL15788371 | 0.86 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL13186401 | 0.84 | MAPT (0.65) | ALDH1A1MEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099672-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-20100099672-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-7645881-B2 | Such as tert-Butyl 3-amino-5-ethyl-4,6-dimethylthieno[2,3-B]pyridine-2-carboxylate which inhibits replication | PTC THERAPEUTICS, INC. (US) | 2010-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099672-A1 | METHODS FOR TREATING HEPATITIS C | OAT, HAVCR2, HCCS | ALDH1A1 539/4885MEN1 4824/4885KMT2A 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.