Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 2/20 | 0.55 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 12/20 | 0.43 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13393767 | 1.00 | XIAP (0.55) | XIAPMLXTAAR1BIRC2ELANE | |
| SCHEMBL13393703 | 0.91 | XIAP (0.53) | XIAPMLXTAAR1BIRC2ELANE | |
| SCHEMBL13393685 | 0.87 | XIAP (0.52) | XIAPMLXTAAR1BIRC2ELANE | |
| SCHEMBL13379994 | 0.86 | XIAP (0.49) | XIAPMLXTAAR1BIRC2ELANE | |
| SCHEMBL13393690 | 0.84 | PKM (0.57) | XIAPMLXTAAR1BIRC2ELANE | |
| SCHEMBL13393858 | 0.84 | XIAP (0.53) | XIAPMLXTAAR1ELANEF2 | |
| SCHEMBL13393698 | 0.84 | XIAP (0.77) | XIAPMLXTAAR1BIRC2ELANE | |
| SCHEMBL13393918 | 0.84 | XIAP (0.77) | XIAPMLXTAAR1BIRC2ELANE | |
| SCHEMBL13393688 | 0.84 | XIAP (0.53) | XIAPMLXTAAR1BIRC2ELANE | |
| SCHEMBL13393679 | 0.84 | PKM (0.57) | XIAPMLXTAAR1BIRC2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093645-A1 | SMAC Peptidomimetics and the Uses Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093645-A1 | SMAC Peptidomimetics and the Uses Thereof | BID, AIFM1, BAD | XIAP 21/4885MLX 758/4885TAAR1 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.