Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13397474 | 0.96 | HRH3 (0.46) | HRH3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13397351 | 0.94 | HRH3 (0.50) | HRH3MEN1KMT2AMAPT | |
| SCHEMBL26267230 | 0.91 | MEN1 (0.39) | HRH3MEN1KMT2A | |
| SCHEMBL13397441 | 0.86 | MEN1 (0.44) | HRH3MEN1KMT2ASIGMAR1 | |
| SCHEMBL13397392 | 0.85 | PAOX (0.40) | HRH3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12790350 | 0.82 | MEN1 (0.44) | HRH3MEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL12790355 | 0.82 | KEAP1 (0.48) | HRH3ALDH1A1SIGMAR1 | |
| SCHEMBL25887137 | 0.82 | MAOB (0.43) | HRH3MEN1KMT2A | |
| SCHEMBL28984366 | 0.81 | TP53 (0.39) | MEN1KMT2A | |
| SCHEMBL13397506 | 0.81 | HRH3 (0.39) | HRH3MEN1KMT2AMAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | HRH3 1893/4885MEN1 4734/4885KMT2A 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.