Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PER2 | O15055 | 1/20 | 0.38 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316244 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTTP53PIK3CDEPHX2 | |
| SCHEMBL13397341 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTTP53PIK3CDEPHX2 | |
| SCHEMBL13397270 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTTP53PIK3CDEPHX2 | |
| SCHEMBL13397444 | 0.78 | GAA (0.44) | ALDH1A1MAPTTP53PIK3CDHTT | |
| SCHEMBL4550247 | 0.77 | L3MBTL3 (0.58) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL19702056 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTTP53PIK3CDEPHX2 | |
| SCHEMBL19419455 | 0.76 | NPY5R (0.43) | ALDH1A1MAPTPIK3CDEPHX2EPHX1 | |
| SCHEMBL24316254 | 0.76 | L3MBTL3 (0.41) | ALDH1A1MAPTTP53EPHX2GAA | |
| SCHEMBL16376310 | 0.75 | HPGD (0.51) | ALDH1A1MAPTEPHX1HTTKDM4E | |
| SCHEMBL19710577 | 0.75 | KDM4E (0.45) | ALDH1A1EPHX2EPHX1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | ALDH1A1 474/4885MAPT 3659/4885TP53 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.