Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15457022 | 0.86 | PKM (0.46) | HTTPKMHPGDKMT2AMAPT | |
| SCHEMBL13397950 | 0.84 | MAPT (0.38) | HTTPKMHPGDKMT2AMAPT | |
| SCHEMBL13397921 | 0.84 | HTT (0.57) | HTTPKMHPGDMAPTLMNA | |
| SCHEMBL20414407 | 0.82 | KMT2A (0.53) | KMT2AMAPTMEN1LMNAKDM4E | |
| SCHEMBL1702667 | 0.82 | MAPT (0.57) | HPGDKMT2AMAPTMEN1LMNA | |
| SCHEMBL30873770 | 0.82 | MAPT (0.57) | HPGDKMT2AMAPTMEN1LMNA | |
| SCHEMBL9160237 | 0.81 | MEN1 (0.46) | HTTPKMKMT2AMAPTMEN1 | |
| SCHEMBL13397756 | 0.79 | LTA4H (0.57) | HTTPKMHPGDKMT2AMAPT | |
| SCHEMBL13321959 | 0.79 | LTA4H (0.40) | HTTPKMHPGDKMT2AMAPT | |
| SCHEMBL13397754 | 0.79 | HTT (0.49) | HTTPKMHPGDLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642165-B2 | Organic-inorganic hybrid composition | FUJIFILM CORPORATION (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20100104842-A1 | ORGANIC-INORGANIC HYBRID COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |