⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17282285 | 0.79 | KMT2A (0.31) | — | |
| SCHEMBL17271999 | 0.78 | — | — | |
| SCHEMBL2220219 | 0.75 | POLB (0.31) | — | |
| SCHEMBL14369997 | 0.75 | — | — | |
| SCHEMBL12065417 | 0.75 | — | — | |
| SCHEMBL12066301 | 0.75 | ESR2 (0.33) | — | |
| SCHEMBL4285979 | 0.74 | FOS (0.34) | — | |
| SCHEMBL12374764 | 0.74 | CHRM2 (0.35) | — | |
| SCHEMBL14341339 | 0.72 | TSHR (0.39) | — | |
| SCHEMBL17511416 | 0.71 | PRKCA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010037723-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2010-04-08 | — | — | WO | disclosed |