SCHEMBL13400018

SCHEMBL13400018

C=C(C)C(=O)Nc1ccc2c(c1)n1n(-c3cc(C(C)(C)CC)ccc3O)n21

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 1/20 0.36
▸ POLB P06746 3/20 0.35
▸ TDP1 Q9NUW8 2/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ RECQL P46063 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ MAPT P10636 2/20 0.31
▸ HSD17B10 Q99714 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ BAZ1A Q9NRL2 1/20 0.31
▸ TP53 P04637 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400020 0.91 RXFP1 (0.35) RXFP1POLBTDP1L3MBTL1RECQL
SCHEMBL813234 0.89 RXFP1 (0.39) RXFP1POLBTDP1L3MBTL1RECQL
SCHEMBL13159254 0.89 RXFP1 (0.39) RXFP1POLBTDP1L3MBTL1RECQL
SCHEMBL13400019 0.86 TGM2 (0.38) —
SCHEMBL13159251 0.83 TDP1 (0.40) RXFP1POLBTDP1L3MBTL1RECQL
SCHEMBL812887 0.83 TDP1 (0.40) RXFP1POLBTDP1L3MBTL1RECQL
SCHEMBL812884 0.82 RXFP1 (0.41) RXFP1POLBTDP1L3MBTL1RECQL
SCHEMBL13159250 0.82 RXFP1 (0.41) RXFP1POLBTDP1L3MBTL1RECQL
SCHEMBL812948 0.79 TDP1 (0.45) RXFP1POLBTDP1L3MBTL1RECQL
SCHEMBL13159249 0.79 TDP1 (0.45) RXFP1POLBTDP1L3MBTL1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100103352-A1 OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
US-20100103352-A1 OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
US-20100104775-A1 ULTRAVIOLET ABSORBING POLYMER, CELLULOSE ESTER OPTICAL FILM, METHOD OF PRODUCING CELLULOSE ESTER OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
US-20100104775-A1 ULTRAVIOLET ABSORBING POLYMER, CELLULOSE ESTER OPTICAL FILM, METHOD OF PRODUCING CELLULOSE ESTER OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
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