SCHEMBL13400019

SCHEMBL13400019

C=CC(=O)Nc1ccc2c(c1)n1n(-c3cc(C(C)(C)CC)ccc3O)n21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 9/20 0.38
▸ EGFR P00533 3/20 0.36
▸ FYN P06241 1/20 0.36
▸ SRC P12931 1/20 0.36
▸ NOX1 Q9Y5S8 1/20 0.35
▸ JAK3 P52333 2/20 0.35
▸ JAK2 O60674 1/20 0.35
▸ THRA P10827 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ GSTO1 P78417 1/20 0.34
▸ TRPV1 Q8NER1 1/20 0.34
▸ F13A1 P00488 3/20 0.33
▸ TGM1 P22735 3/20 0.33
▸ TGM3 Q08188 2/20 0.33
▸ LMNA P02545 1/20 0.33
▸ BRD4 O60885 1/20 0.32
▸ ACKR3 P25106 1/20 0.32
▸ PPARG P37231 1/20 0.32
▸ ERBB2 P04626 1/20 0.32
▸ TEC P42680 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400018 0.86 RXFP1 (0.36) —
SCHEMBL13400024 0.80 CA12 (0.32) —
SCHEMBL13159260 0.78 TGM2 (0.44) TGM2EGFRNOX1GSTO1F13A1
SCHEMBL813101 0.78 TGM2 (0.44) TGM2EGFRNOX1GSTO1F13A1
SCHEMBL812908 0.78 EGFR (0.40) TGM2EGFRFYNSRCNOX1
SCHEMBL13159257 0.78 EGFR (0.40) TGM2EGFRFYNSRCNOX1
SCHEMBL13400041 0.78 KDM4E (0.34) THRB
SCHEMBL13400020 0.77 RXFP1 (0.35) LMNA
SCHEMBL813234 0.74 RXFP1 (0.39) TRPV1
SCHEMBL13159254 0.74 RXFP1 (0.39) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100103352-A1 OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
US-20100103352-A1 OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
US-20100104775-A1 ULTRAVIOLET ABSORBING POLYMER, CELLULOSE ESTER OPTICAL FILM, METHOD OF PRODUCING CELLULOSE ESTER OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
US-20100104775-A1 ULTRAVIOLET ABSORBING POLYMER, CELLULOSE ESTER OPTICAL FILM, METHOD OF PRODUCING CELLULOSE ESTER OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
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