Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629366 | 0.80 | NOTUM (0.63) | HPGDSMN1; SMN2NOTUMABL1ALDH1A1 | |
| SCHEMBL16472348 | 0.78 | SMN1; SMN2 (0.61) | HPGDSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL25692790 | 0.78 | HPGD (0.47) | HPGDSMN1; SMN2ABL1ALDH1A1MAPK1 | |
| SCHEMBL9605475 | 0.77 | PTK2 (0.47) | MAPTNPC1RAB9AKDM4E | |
| SCHEMBL13595280 | 0.74 | NPC1 (0.39) | SMN1; SMN2ABL1ALDH1A1NPC1RAB9A | |
| SCHEMBL16478650 | 0.72 | RAB9A (0.62) | SMN1; SMN2MAPTNPC1RAB9AKDM4E | |
| SCHEMBL6613670 | 0.71 | RAB9A (0.62) | HPGDSMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL12229596 | 0.71 | SMN1; SMN2 (0.56) | HPGDSMN1; SMN2ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL25693116 | 0.71 | HPGD (0.52) | HPGDSMN1; SMN2ABL1ALDH1A1MAPK1 | |
| SCHEMBL16472460 | 0.69 | RAB9A (0.52) | HPGDSMN1; SMN2ALDH1A1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700774-B2 | Heterocyclic compounds and their pharmaceutical compositions | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-04-20 | — | — | US | disclosed |