SCHEMBL6613670

SCHEMBL6613670

COCC(=O)Nc1ccc(Br)cn1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.62
TSHR P16473 3/20 0.61
HPGD P15428 1/20 0.59
NPC1 O15118 4/20 0.57
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
LMNA P02545 1/20 0.53
POLB P06746 2/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26016838 0.86 RAB9A (0.50) RAB9ATSHRHPGDNPC1MEN1
SCHEMBL6613815 0.85 RAB9A (0.59) RAB9ATSHRNPC1MEN1KMT2A
SCHEMBL16478650 0.83 RAB9A (0.62) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL7030047 0.82 RAB9A (0.72) RAB9ATSHRNPC1MEN1KMT2A
SCHEMBL14784228 0.82 TSHR (0.71) RAB9ATSHRHPGDNPC1MEN1
SCHEMBL29251156 0.81 TDP1 (0.67) RAB9ATSHRNPC1MEN1KMT2A
SCHEMBL15004187 0.80 TSHR (0.69) RAB9ATSHRNPC1MEN1KMT2A
SCHEMBL5689000 0.80 RAB9A (0.60) RAB9ATSHRNPC1MEN1KMT2A
SCHEMBL4775518 0.79 RAB9A (0.83) RAB9ATSHRNPC1MEN1KMT2A
SCHEMBL16472460 0.79 RAB9A (0.52) RAB9ATSHRHPGDNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289984-A4 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM CO LTD (KR) 2004-11-24 EP disclosed
US-6689779-B2 PYRIDINE OR PYRIMIDINE SUBSTITUTED; ANTIBACTERIAL ACTIVITY; LOW TOXICITY DONG A PHARM. CO., LTD. (KR) 2004-02-10 US disclosed
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof DONG A PHARM. CO., LTD. (KR) 2003-09-04 US disclosed
EP-1289984-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF Dong A Pharmaceutical Co. Ltd. (KR) 2003-03-12 EP disclosed
WO-2001094342-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM. CO., LTD. (KR) 2001-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof OXA1L, ODC1, PDCD4 RAB9A 3208/4885TSHR 3527/4885HPGD 1495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.