Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252356 | 0.83 | CES2 (0.48) | CES2CYP26A1CYP24A1AHRPTGS1 | |
| SCHEMBL17969187 | 0.80 | CES2 (0.43) | CES2APPCYP26A1CYP24A1PTGS1 | |
| SCHEMBL16398302 | 0.80 | CES2 (0.43) | CES2APPCYP26A1CYP24A1PTGS1 | |
| SCHEMBL3432404 | 0.79 | CES2 (0.46) | CES2CYP26A1CYP24A1PTPN5BACE1 | |
| SCHEMBL663646 | 0.79 | CES2 (0.50) | CES2CYP26A1CYP24A1PTPN5BACE1 | |
| SCHEMBL9996688 | 0.79 | CES2 (0.46) | CES2CYP26A1CYP24A1AHRPTGS1 | |
| SCHEMBL4325947 | 0.78 | CES2 (0.50) | CES2BACE1NFKB1KDM4ECYP1A2 | |
| SCHEMBL4325950 | 0.78 | CES2 (0.50) | CES2BACE1NFKB1KDM4ECYP1A2 | |
| SCHEMBL18002921 | 0.77 | NFE2L2 (0.44) | CES2APPNQO2NFE2L2 | |
| SCHEMBL5220846 | 0.75 | CES2 (0.42) | CES2CYP26A1CYP24A1PTGS1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700366-B2 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-04-20 | — | — | US | disclosed |
| US-7700366-B2 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-04-20 | — | — | US | disclosed |