SCHEMBL13400970

SCHEMBL13400970

Cc1ccc(C(=O)Nc2cc(C(C)(C)c3ccc(C)c(NC(=O)c4ccc(C)c(C)c4)c3)ccc2C)cc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
MEN1 O00255 2/20 0.56
HDAC1 Q13547 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
HTT P42858 2/20 0.54
HPGD P15428 2/20 0.54
RAB9A P51151 5/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
PPARG P37231 1/20 0.51
NPC1 O15118 4/20 0.48
CASP3 P42574 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
LDLR P01130 1/20 0.47
APOBEC3A P31941 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001969 0.90 KMT2A (0.52) KMT2AMEN1HDAC1HDAC8HDAC6
SCHEMBL13213988 0.84 KMT2A (0.52) KMT2AMEN1HDAC1HDAC8HDAC6
SCHEMBL22746195 0.83 NPC1 (0.63) KMT2AMEN1HDAC8HDAC6HTT
SCHEMBL13400972 0.81 KMT2A (0.62) KMT2AMEN1HDAC1HDAC8HDAC6
SCHEMBL2605528 0.78 MEN1 (0.52) KMT2AMEN1HDAC1HTTRAB9A
SCHEMBL12847635 0.78 MEN1 (0.77) KMT2AMEN1HDAC1HDAC8HDAC6
SCHEMBL7304022 0.77 HTT (0.67) KMT2AHDAC1HDAC8HDAC6HTT
SCHEMBL25721410 0.77 HDAC6 (0.67) KMT2AMEN1HDAC8HDAC6RAB9A
SCHEMBL21588673 0.77 HDAC6 (0.67) KMT2AMEN1HDAC8HDAC6RAB9A
SCHEMBL22580567 0.76 TDP1 (0.66) KMT2AMEN1RAB9AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673540-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2014-03-18 US disclosed
US-20130095426-A1 PHOTOSENSITIVE POLYMIDES ETERNAL CHEMICAL CO., LTD. (TW) 2013-04-18 US disclosed
US-8349539-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2013-01-08 US disclosed
US-20100086874-A1 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2010-04-08 US disclosed