Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.64 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388808 | 0.89 | APOBEC3A (0.71) | HTTHPGDAPOBEC3AAPOBEC3GNPSR1 | |
| SCHEMBL7302035 | 0.88 | NR1H4 (0.67) | HTTHPGDNR1H4PPARGKCNK3 | |
| SCHEMBL7300963 | 0.86 | KCNMA1 (0.71) | HTTHPGDNR1H4TP53SMN1; SMN2 | |
| SCHEMBL15135742 | 0.86 | NPC1 (0.61) | HTTHPGDNR1H4NPSR1TP53 | |
| SCHEMBL7295300 | 0.85 | HPGD (0.64) | HTTHPGDNR1H4PPARGTP53 | |
| SCHEMBL7302258 | 0.85 | HPGD (0.64) | HTTHPGDNR1H4PPARGTP53 | |
| SCHEMBL7293409 | 0.85 | SERPINE1 (0.67) | HTTHPGDNR1H4PPARGSMN1; SMN2 | |
| SCHEMBL26074394 | 0.85 | ALDH1A1 (0.66) | HTTHPGDNR1H4PPARGSMN1; SMN2 | |
| SCHEMBL23409003 | 0.84 | APOBEC3A (0.66) | HTTHPGDAPOBEC3AAPOBEC3GNPSR1 | |
| SCHEMBL9132247 | 0.84 | HPGD (0.62) | HTTHPGDNR1H4PPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |