Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907412 | 1.00 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL19844211 | 0.96 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL13401006 | 0.95 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL10073448 | 0.94 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL14907417 | 0.93 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL13400976 | 0.93 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL10073832 | 0.92 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL13400989 | 0.92 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL15480715 | 0.91 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL3478348 | 0.88 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | CUTA, MC1R, CTSG | TSHR 3118/4885HPGD 456/4885ALDH1A1 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.