SCHEMBL13402127

SCHEMBL13402127

CCCCCOCCCCOc1ccc(-c2ccc(C3CCC(C4CCC(C)CC4)CC3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.48
RARB P10826 4/20 0.44
HRH3 Q9Y5N1 6/20 0.44
LMNA P02545 1/20 0.43
CYP2C9 P11712 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 1/20 0.41
S1PR3 Q99500 1/20 0.40
HRH2 P25021 1/20 0.40
HRH1 P35367 1/20 0.40
NR5A1 Q13285 1/20 0.40
P2RY14 Q15391 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13402152 0.94 RARB (0.51) RAB9ARARBHRH3LMNACYP2C9
SCHEMBL11276971 0.93 RAB9A (0.53) RAB9ARARBHRH3LMNACYP2C9
SCHEMBL11287135 0.92 RAB9A (0.52) RAB9ARARBHRH3LMNACYP2C9
SCHEMBL11279143 0.92 RAB9A (0.52) RAB9ARARBHRH3LMNACYP2C9
SCHEMBL11285243 0.92 RAB9A (0.52) RAB9ARARBHRH3LMNACYP2C9
SCHEMBL11274828 0.92 RAB9A (0.52) RAB9ARARBHRH3LMNACYP2C9
SCHEMBL11283562 0.92 RAB9A (0.52) RAB9ARARBHRH3LMNACYP2C9
SCHEMBL11277730 0.92 RAB9A (0.52) RAB9ARARBHRH3LMNACYP2C9
SCHEMBL13402069 0.92 RAB9A (0.52) RAB9AHRH3LMNACYP2C9HPGD
SCHEMBL11302126 0.92 RAB9A (0.52) RAB9ARARBHRH3LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7705105-B2 A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; CHISSO PETROCHEMICAL CORPORATION (JP) 2010-04-27 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed