Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276971 | 0.95 | RAB9A (0.53) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL13402127 | 0.94 | RAB9A (0.48) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL11285243 | 0.93 | RAB9A (0.52) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL11279143 | 0.93 | RAB9A (0.52) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL11302126 | 0.93 | RAB9A (0.52) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL11274828 | 0.93 | RAB9A (0.52) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL11277730 | 0.93 | RAB9A (0.52) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL11287135 | 0.93 | RAB9A (0.52) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL11283562 | 0.93 | RAB9A (0.52) | RARBRAB9AHRH3LMNACYP3A4 | |
| SCHEMBL11277004 | 0.92 | RAB9A (0.56) | RARBRAB9AHRH3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |