SCHEMBL1340249

SCHEMBL1340249

CC1=C(Br)C(=O)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL78279 0.95
SCHEMBL161507 0.69
SCHEMBL5405236 0.67
SCHEMBL12786389 0.65
SCHEMBL10455224 0.65
SCHEMBL112009 0.65
SCHEMBL677601 0.65
SCHEMBL6738847 0.65 TYR (0.39)
SCHEMBL12135406 0.65
SCHEMBL14594115 0.63 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673321-B9 METHOD OF PREPARING FULVENE COMPOUNDS AND METHOD OF PREPARING ANSA-METALLOCENE COMPOUNDS USING THE COMPOUNDS LG CHEMICAL LTD (KR) 2015-04-22 EP claimed
EP-1673321-B1 METHOD OF PREPARING FULVENE COMPOUNDS AND METHOD OF PREPARING ANSA-METALLOCENE COMPOUNDS USING THE COMPOUNDS LG CHEMICAL LTD (KR) 2014-09-17 EP claimed
US-7166731-B2 Method of preparing fulvene compounds and method of preparing ansa-metallocene compounds using the compounds LG CHEM. LTD. (KR) 2007-01-23 US claimed
US-20050080296-A1 Method of preparing fulvene compounds and method of preparing ansa-metallocene compounds using the compounds LG CHEM. LTD. (KR) 2005-04-14 US claimed
US-9643919-B2 Cycloalkyl-dione derivatives and methods of their use THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2017-05-09 US disclosed
US-20160168188-A1 SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF PREVACUS, INC. 2016-06-16 US disclosed
US-20160168188-A1 SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF PREVACUS, INC. 2016-06-16 US disclosed
US-20160108081-A1 SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF PREVACUS INC (US) 2016-04-21 US disclosed
US-20160108081-A1 SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF PREVACUS INC (US) 2016-04-21 US disclosed
EP-1532181-B1 FULVENE AND PREPARATION THEREOF LG CHEMICAL LTD (KR) 2016-03-16 EP disclosed
US-20160031805-A1 CYCLOALKYL-DIONE DERIVATIVES AND METHODS OF THEIR USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-02-04 US disclosed
US-20160016988-A1 SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF UNIV FLORIDA STATE RES FOUND (US) 2016-01-21 US disclosed
EP-1532181-A1 FULVENE, METALLOCENE CATALYSTS AND PREPARATION METHOD THEREOF, AND PREPARATION OF POLYOLEFINES COPOLYMER USING THE SAME LG Chem, Ltd. (KR) 2005-05-25 EP disclosed
US-20050080296-A1 Method of preparing fulvene compounds and method of preparing ansa-metallocene compounds using the compounds LG CHEM. LTD. (KR) 2005-04-14 US disclosed
US-20050075366-A1 4-(2-Methyl-5,6,7,8-tetrahydro-quinolin-7-ylmethyl)-1,3-dihydro-imidazole-2-thione as specific alpha2B agonist and methods of using the same ALLERGAN, INC. 2005-04-07 US disclosed
EP-1507767-A1 4-SUBSTITUTED IMIDAZOLE-2-THIONES AND IMIDAZOL-2-ONES AS AGONISTS OF THE ALPHA-2B AND ALPHA-2C ADRENERGIC RECEPTORS Allergan, Inc. (US) 2005-02-23 EP disclosed
US-20050004385-A1 Fulvene, metallocene catalysts and preparation method thereof, and preparation of polyolefines copolymer using the same LG CHEM, LTD. (KR) 2005-01-06 US disclosed
US-20040220402-A1 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds ALLERGAN, INC. 2004-11-04 US disclosed
WO-2004020481-A1 FULVENE, METALLOCENE CATALYSTS AND PREPARATION METHOD THEREOF, AND PREPARATION OF POLYOLEFINES COPOLYMER USING THE SAME LG CHEM, LTD. (KR) 2004-03-11 WO disclosed
WO-2003099795-A1 4-SUBSTITUTED IMIDAZOLE-2-THIONES AND IMIDAZOL-2-ONES AS AGONISTS OF THE ALPHA-2B AND ALPHA-2C ADRENERGIC RECEPTORS ALLERGAN, INC. (US) 2003-12-04 WO disclosed