Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079729 | 0.93 | HDAC1 (0.48) | HDAC1HDAC2TDP1CHRM1AKR1A1 | |
| SCHEMBL5079726 | 0.93 | HDAC1 (0.48) | HDAC1HDAC2TDP1CHRM1AKR1A1 | |
| SCHEMBL678102 | 0.87 | SLC22A6 (0.45) | HDAC1HDAC2TDP1GPR84LMNA | |
| SCHEMBL5077882 | 0.87 | SLC22A6 (0.45) | HDAC1HDAC2TDP1GPR84LMNA | |
| SCHEMBL28711690 | 0.87 | GPR84 (0.46) | HDAC1HDAC2TDP1CHRM1AKR1A1 | |
| SCHEMBL5879044 | 0.86 | GPR84 (0.53) | GPR84CA2MAPK1SLC22A6TSHR | |
| SCHEMBL27945267 | 0.85 | SLC22A6 (0.43) | HDAC1HDAC2TDP1GPR84LMNA | |
| SCHEMBL27753421 | 0.85 | SLC22A6 (0.43) | HDAC1HDAC2TDP1GPR84LMNA | |
| SCHEMBL5516785 | 0.81 | HDAC1 (0.42) | HDAC1HDAC2TDP1CHRM1AKR1A1 | |
| SCHEMBL2327830 | 0.80 | METAP1 (0.41) | HDAC1HDAC2TDP1CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087561-A1 | VISCOELASTIC POLYURETHANE FOAMS COMPRISING AMIDATED OR TRANSESTERIFIED OLIGOMERIC NATURAL OIL POLYOLS | CARGILL, INCORPORATED (US) | 2010-04-08 | — | — | US | disclosed |