Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678102 | 1.00 | SLC22A6 (0.45) | SLC22A6FFAR3TDP1SMN1; SMN2GPR84 | |
| SCHEMBL27945267 | 0.97 | SLC22A6 (0.43) | SLC22A6FFAR3TDP1SMN1; SMN2GPR84 | |
| SCHEMBL27753421 | 0.97 | SLC22A6 (0.43) | SLC22A6FFAR3TDP1SMN1; SMN2GPR84 | |
| SCHEMBL17066267 | 0.89 | TDP1 (0.42) | SLC22A6FFAR3TDP1SMN1; SMN2GPR84 | |
| SCHEMBL9059911 | 0.87 | SLC22A6 (0.42) | SLC22A6FFAR3TDP1SMN1; SMN2GPR84 | |
| SCHEMBL13403131 | 0.87 | HDAC1 (0.42) | SLC22A6FFAR3TDP1GPR84HDAC3 | |
| SCHEMBL1572826 | 0.86 | SMN1; SMN2 (0.42) | SLC22A6FFAR3TDP1SMN1; SMN2GPR84 | |
| SCHEMBL446451 | 0.86 | SLC22A6 (0.46) | SLC22A6FFAR3TDP1SMN1; SMN2GPR84 | |
| SCHEMBL14359750 | 0.85 | FOLH1 (0.46) | FFAR3GPR84HDAC3HDAC1HDAC2 | |
| SCHEMBL18222806 | 0.84 | MME (0.39) | SLC22A6FFAR3TDP1SMN1; SMN2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912936-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | Pharmacia & Upjohn Company LLC (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2007010387-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-25 | — | — | WO | claimed |
| EP-1912936-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | Pharmacia & Upjohn Company LLC (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007010387-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-25 | — | — | WO | disclosed |