Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LOX | P28300 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13404363 | 0.98 | ALDH1A1 (0.58) | ALDH1A1CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13404373 | 0.85 | TSHR (0.51) | ALDH1A1CNR1KMT2AL3MBTL1TSHR | |
| SCHEMBL19259699 | 0.80 | CNR1 (0.59) | ALDH1A1CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL19259615 | 0.80 | LOX (0.51) | ALDH1A1CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL12335127 | 0.80 | LOX (0.54) | ALDH1A1CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13743077 | 0.78 | L3MBTL1 (0.58) | ALDH1A1CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13742871 | 0.78 | GAA (0.65) | ALDH1A1TSHRGAALMNASMN1; SMN2 | |
| SCHEMBL5366600 | 0.78 | MAPT (0.58) | ALDH1A1CNR1L3MBTL1LOXTSHR | |
| SCHEMBL13742881 | 0.77 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1TSHRGAALMNA | |
| SCHEMBL13404368 | 0.77 | L3MBTL1 (0.62) | ALDH1A1KMT2AL3MBTL1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087432-A1 | PYRROLE DERIVATIVES HAVING CRTH2 RECEPTOR ANTAGONIST ACTIVITY | NOVARTIS AG (CH) | 2010-04-08 | — | — | US | disclosed |
| US-20100087432-A1 | PYRROLE DERIVATIVES HAVING CRTH2 RECEPTOR ANTAGONIST ACTIVITY | NOVARTIS AG (CH) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087432-A1 | PYRROLE DERIVATIVES HAVING CRTH2 RECEPTOR ANTAGONIST ACTIVITY | PRLHR, AVPR2, CRHR2 | ALDH1A1 3117/4885CNR1 77/4885MEN1 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.