Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367219 | 0.86 | LMNA (0.56) | LMNAMTNR1AMTNR1BALDH1A1ALOX5 | |
| SCHEMBL4367213 | 0.86 | LMNA (0.56) | LMNAMTNR1AMTNR1BALDH1A1ALOX5 | |
| SCHEMBL4372465 | 0.86 | LMNA (0.56) | LMNAMTNR1AMTNR1BALDH1A1ALOX5 | |
| SCHEMBL13883457 | 0.83 | MTNR1A (0.60) | LMNAMTNR1AMTNR1BALOX5OR51E2 | |
| SCHEMBL3251828 | 0.82 | LMNA (0.55) | LMNAALDH1A1THRBKMT2AGAA | |
| SCHEMBL6418730 | 0.80 | MTNR1A (0.66) | LMNAMTNR1AMTNR1BALDH1A1ALOX5 | |
| SCHEMBL14432087 | 0.80 | KMT2A (0.66) | LMNAMTNR1AMTNR1BALDH1A1ALOX5 | |
| SCHEMBL4363542 | 0.78 | GAA (0.55) | MTNR1AMTNR1BALOX5OR51E2KMT2A | |
| SCHEMBL4372703 | 0.78 | GAA (0.55) | MTNR1AMTNR1BALOX5OR51E2KMT2A | |
| SCHEMBL4363659 | 0.78 | GAA (0.55) | MTNR1AMTNR1BALOX5OR51E2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700522-B2 | α-Oxygenated or α-thiolated carboxylic acid phenethylamide derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2010-04-20 | — | — | US | disclosed |