Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969992 | 0.84 | CSF1R (0.52) | CSF1RALDH1A1GAAHTTMAPK10 | |
| SCHEMBL20598140 | 0.81 | ALDH1A1 (0.67) | CSF1RALDH1A1GAAHTTMAPK10 | |
| SCHEMBL13405629 | 0.77 | CSF1R (0.90) | CSF1R | |
| SCHEMBL13405632 | 0.77 | CSF1R (0.90) | CSF1R | |
| SCHEMBL23293311 | 0.76 | CSF1R (0.88) | CSF1R | |
| SCHEMBL13405631 | 0.76 | CSF1R (1.00) | CSF1R | |
| SCHEMBL31157967 | 0.76 | CSF1R (1.00) | CSF1R | |
| SCHEMBL31157983 | 0.76 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405634 | 0.75 | CSF1R (1.00) | CSF1R | |
| SCHEMBL3964086 | 0.74 | CSF1R (0.85) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |