Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 15/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405648 | 0.84 | CSF1R (0.68) | CSF1RGAAALDH1A1HTTMAPK10 | |
| SCHEMBL3965919 | 0.76 | CSF1R (0.64) | CSF1RKMT2AMEN1 | |
| SCHEMBL3969505 | 0.76 | CSF1R (0.64) | CSF1R | |
| SCHEMBL3962001 | 0.75 | CSF1R (0.73) | CSF1R | |
| Hydrochloric Acid SCHEMBL3965907 | 0.74 | CSF1R (0.72) | CSF1R | |
| SCHEMBL3971347 | 0.74 | CSF1R (0.74) | CSF1R | |
| SCHEMBL3970795 | 0.74 | CSF1R (0.61) | CSF1R | |
| SCHEMBL20598140 | 0.68 | ALDH1A1 (0.67) | CSF1RGAAALDH1A1HTTMAPK10 | |
| SCHEMBL3967107 | 0.68 | CSF1R (0.64) | CSF1R | |
| SCHEMBL3964666 | 0.68 | CSF1R (0.76) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | claimed |