Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 19/20 | 1.00 |
| ▸ | KIT | P10721 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405631 | 0.91 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL31157967 | 0.91 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL31157983 | 0.91 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL13405757 | 0.90 | CSF1R (0.86) | CSF1RKIT | |
| SCHEMBL13405629 | 0.90 | CSF1R (0.90) | CSF1R | |
| SCHEMBL13405640 | 0.89 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL31157980 | 0.89 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL5202289 | 0.89 | CSF1R (1.00) | CSF1R | |
| SCHEMBL4201294 | 0.85 | CSF1R (0.74) | CSF1RKIT | |
| SCHEMBL3969306 | 0.83 | CSF1R (0.88) | CSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | disclosed |