Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405640 | 0.91 | CSF1R (1.00) | CSF1R | |
| SCHEMBL31157980 | 0.91 | CSF1R (1.00) | CSF1R | |
| SCHEMBL31157978 | 0.90 | CSF1R (0.81) | CSF1R | |
| SCHEMBL13405642 | 0.90 | CSF1R (0.81) | CSF1R | |
| SCHEMBL13405643 | 0.89 | CSF1R (0.83) | CSF1R | |
| SCHEMBL13405751 | 0.89 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405629 | 0.88 | CSF1R (0.90) | CSF1R | |
| SCHEMBL13405644 | 0.87 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405645 | 0.87 | CSF1R (1.00) | CSF1R | |
| SCHEMBL3964503 | 0.85 | CSF1R (0.75) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |
| EP-1807407-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047504-A1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |