SCHEMBL134062

SCHEMBL134062

Br[CH]c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17377333 0.81 ALDH1A1 (0.38)
SCHEMBL1641281 0.76
SCHEMBL13704159 0.76
SCHEMBL331174 0.76
SCHEMBL5158829 0.76 MAOA (0.44)
Phosphine SCHEMBL7763948 0.73 MAOB (0.58)
Hydrogen Sulfide SCHEMBL30522465 0.73 MAOB (0.58)
SCHEMBL5022819 0.73 MAOB (0.58)
SCHEMBL218845 0.71
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.69 MAOB (0.73)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6411 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344248-A 20-Deoxyingenol ether derivative with anti-tumor activity and preparation and application thereof 沈阳药科大学 2024-07-16 CN claimed
CN-114957327-B Synthesis method of tetraphosphine ligand based on benzene 广东欧凯新材料有限公司 2024-07-09 CN claimed
CN-116730932-B Preparation and application of propylene pimaric (1-o-nitrobenzyl-5-o-nitrobenzyl sulfide) -1,2, 4-triazole 西北农林科技大学 2024-06-18 CN claimed
CN-118215665-A Beta-lactamase inhibitor intermediate and preparation method thereof 苏州信诺维医药科技股份有限公司 2024-06-18 CN claimed
CN-117986202-B 1,2, 4-Thiadiazolidine-3, 5-dione compound with PTPN2 inhibitory activity, and preparation method and application thereof 中国药科大学 2024-06-14 CN claimed
CN-118164845-A Preparation method of beipezite 山东铂源药业股份有限公司 2024-06-11 CN claimed
CN-114634498-B Pleuromutilin derivative containing thiazole-pyridine benzyl quaternary ammonium salt side chain and preparation method and application thereof 西咸新区沣厚原创医药科技有限公司 2024-06-04 CN claimed
CN-115160250-B 4, 6-Biphenol derivative and application thereof 沈阳药科大学 2024-06-04 CN claimed
CN-115521254-B Indanterol derivative and preparation method and application thereof 中国药科大学 2024-05-31 CN claimed
CN-114539098-B Difunctional HDAC6 inhibitor, synthesis method and application 青岛大学 2024-05-24 CN claimed
EP-0008497-A1 Beta-lactam-containing compounds, their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1980-03-05 EP claimed
US-4189550-A HYDROXYALKYL AMINE COMPOUNDS AND SALTS DEUTSCHE GOLD- UND SILBER-SCHEINDEANSTALT VORMALS ROESSLER (DE) 1980-02-19 US claimed
US-4172197-A BACTERICIDES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-10-23 US claimed
EP-0002320-A1 Process for the preparation of clavulanic acid derivatives and compounds used as intermediates therein BEECHAM GROUP PLC (GB) 1979-06-13 EP claimed
EP-0001682-A2 Heterocyclic compounds and their use as pesticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-05-02 EP claimed
US-4070531-A DIHYDROXYPROPYLAMINE DERIVATIVES DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1978-01-24 US claimed
US-4015974-A HERBICIDES, INSECTICIDES, NEMATOCIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-04-05 US claimed
US-3989451-A AZO DYESTUFFS AMERICAN COLOR & CHEMICAL CORPORATION (US) 1976-11-02 US claimed
US-3976469-A Halogenated ketones as herbicide antidotes STAUFFER CHEMICAL COMPANY (US) 1976-08-24 US claimed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed