Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | ESRRG | P62508 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203278 | 0.86 | ANPEP (0.47) | KMT2ALMNA | |
| SCHEMBL28856753 | 0.83 | EPHX2 (0.59) | RAB9ANPC1EPHX2HDAC2HDAC8 | |
| SCHEMBL27687302 | 0.83 | EPHX2 (0.63) | RAB9ANPC1EPHX2HDAC2HDAC8 | |
| SCHEMBL28240820 | 0.81 | EPHX2 (0.61) | RAB9ANPC1EPHX2HDAC2HDAC8 | |
| SCHEMBL751214 | 0.80 | HDAC2 (0.80) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL28193721 | 0.79 | HDAC2 (0.77) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27406375 | 0.78 | NAAA (0.68) | RAB9ANPC1EPHX2HDAC2HDAC8 | |
| SCHEMBL27406374 | 0.78 | NAAA (0.68) | RAB9ANPC1EPHX2HDAC2HDAC8 | |
| SCHEMBL2237718 | 0.78 | EPHX2 (0.65) | RAB9ANPC1EPHX2HDAC2HDAC8 | |
| SCHEMBL2237728 | 0.78 | EPHX2 (0.65) | RAB9ANPC1EPHX2HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705161-B2 | Process for producing nitrogenous 5-membered cyclic compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070191614-A1 | Process for producing nitrogenous 5-membered cyclic compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191614-A1 | Process for producing nitrogenous 5-membered cyclic compound | HRH4, HRH2, HRH1 | RAB9A 435/4885NPC1 2811/4885EPHX2 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.