Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407124 | 0.86 | RAB9A (0.62) | LMNAKMT2A | |
| SCHEMBL3508825 | 0.85 | MMP2 (0.55) | ANPEPPKMRNPEPDNPEP | |
| SCHEMBL4343821 | 0.85 | MMP2 (0.51) | ANPEPERAP1ERAP2MMP8METAP2 | |
| SCHEMBL2637087 | 0.85 | MMP2 (0.51) | ANPEPERAP1ERAP2MMP8METAP2 | |
| SCHEMBL4343818 | 0.85 | MMP2 (0.51) | ANPEPERAP1ERAP2MMP8METAP2 | |
| SCHEMBL893147 | 0.81 | TSHR (0.50) | LMNAPKMMMP8TSHRCNR2 | |
| SCHEMBL4895850 | 0.80 | EPHX1 (0.56) | ANPEPERAP1ERAP2LMNATSHR | |
| Phenethylcarbamic Acid SCHEMBL249525 | 0.78 | CA12 (0.68) | CA12CA2CA9 | |
| SCHEMBL5326561 | 0.77 | S1PR2 (0.65) | ANPEPERAP1ERAP2 | |
| SCHEMBL288869 | 0.77 | S1PR2 (0.65) | ANPEPERAP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088788-B2 | Substituted fused[1,2] imidazo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-03 | — | — | US | disclosed |