Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13391220 | 0.86 | AMY1A (0.39) | AMY1AKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL9524475 | 0.81 | AMY1A (0.60) | AMY1AKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL9727197 | 0.81 | AMY1A (0.60) | AMY1AKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL13408638 | 0.70 | KMT2A (0.59) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9526187 | 0.68 | AMY1A (0.57) | AMY1AKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL9727237 | 0.68 | KDM4E (0.45) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9727241 | 0.68 | KDM4E (0.45) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9528601 | 0.67 | KDM4E (0.44) | AMY1AKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL9525658 | 0.62 | CCKBR (0.38) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL12100471 | 0.62 | MEN1 (0.41) | KMT2AMEN1MAPTL3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | CELTAXSYS, INC. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | PMAIP1, CDC42, DCX | AMY1A 4646/4885KMT2A 4738/4885MEN1 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.