SCHEMBL13408686

SCHEMBL13408686

c1ccc(-n2c3ccccc3c3cc(-c4cc5cc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)c6ccccc6c5c5ccccc45)ccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ATM Q13315 1/20 0.55
PTGER4 P35408 1/20 0.39
KMT2A Q03164 3/20 0.36
IL1R1 P14778 1/20 0.36
HDAC4 P56524 1/20 0.36
ALDH1A1 P00352 5/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 1/20 0.35
TSHR P16473 2/20 0.35
JAK2 O60674 1/20 0.35
JAK3 P52333 1/20 0.35
POLB P06746 1/20 0.35
BRCA1 P38398 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPY5R Q15761 2/20 0.34
MAPK8 P45983 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13408696 0.97 L3MBTL1 (0.51) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL13408825 0.97 L3MBTL1 (0.51) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL13408872 0.93 L3MBTL1 (0.47) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL24742394 0.92 KDM4E (0.49) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL13408893 0.91 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL27365580 0.88 L3MBTL1 (0.51) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL16542831 0.88 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL13409050 0.88 KDM4E (0.53) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL13408793 0.87 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16307757 0.87 L3MBTL1 (0.50) L3MBTL1KDM4EATMPTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
EP-2161319-A2 Benzo(c)phenanthrene derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 L3MBTL1 479/4885KDM4E 4170/4885ATM 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.