SCHEMBL16307757

SCHEMBL16307757

c1ccc(-n2c3ccccc3c3cc(-c4cc5cccc6c(-c7cc8cccc9c(-c%10ccc%11c(c%10)c%10ccccc%10n%11-c%10ccccc%10)cc%10cccc7c%10c89)cc7cccc4c7c56)ccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.50
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
PTGER4 P35408 1/20 0.37
ALDH1A1 P00352 6/20 0.34
KMT2A Q03164 3/20 0.34
TSHR P16473 3/20 0.34
IL1R1 P14778 1/20 0.34
HDAC4 P56524 1/20 0.34
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
RXFP1 Q9HBX9 2/20 0.33
PTGES O14684 1/20 0.33
HSD17B10 Q99714 2/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
POLB P06746 1/20 0.33
BRCA1 P38398 1/20 0.33
NPY5R Q15761 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27365580 0.99 L3MBTL1 (0.51) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL27365680 0.95 L3MBTL1 (0.47) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL16307758 0.94 L3MBTL1 (0.44) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL16295923 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL25916810 0.88 KDM4E (0.41) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL24742394 0.88 KDM4E (0.49) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL13408686 0.87 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL13408893 0.87 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL27365759 0.87 KDM4E (0.48) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL21190613 0.86 L3MBTL1 (0.47) L3MBTL1KDM4EATMPTGER4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014200243-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME SK CHEMICALS CO., LTD. (KR) 2014-12-18 WO disclosed