Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNB1 | Q14721 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.36 |
| ▸ | TUBB | P07437 | 3/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metrafenone SCHEMBL30013482 | 0.92 | ALDH1A1 (0.42) | ALDH1A1KCNB1PTPN1HPGDCYP1A2 | |
| Metrafenone SCHEMBL20788 | 0.92 | ALDH1A1 (0.42) | ALDH1A1KCNB1PTPN1HPGDCYP1A2 | |
| Metrafenone SCHEMBL29408434 | 0.92 | ALDH1A1 (0.42) | ALDH1A1KCNB1PTPN1HPGDCYP1A2 | |
| Metrafenone SCHEMBL1613717 | 0.84 | HPGD (0.52) | ALDH1A1HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6743725 | 0.83 | PTPN1 (0.43) | ALDH1A1PTPN1HPGDTUBB1TUBB4A | |
| SCHEMBL6860817 | 0.83 | POLB (0.44) | ALDH1A1PTPN1HPGDCYP1A2CYP2C19 | |
| Metrafenone SCHEMBL2311489 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KCNB1PTPN1HPGDCYP1A2 | |
| SCHEMBL3762760 | 0.81 | MEN1 (0.39) | ALDH1A1KCNB1PTPN1HPGDERN1 | |
| SCHEMBL7518963 | 0.81 | SMPD1 (0.41) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL6859535 | 0.80 | ELANE (0.37) | ALDH1A1PTPN1HPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105670-A1 | FUNGICIDAL MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105670-A1 | FUNGICIDAL MIXTURES | DEGS1, GMDS, Q6ZSR9 | ALDH1A1 988/4885KCNB1 1149/4885PTPN1 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.