Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409325 | 0.81 | BTK (0.52) | BTKMAPTATML3MBTL1TSHR | |
| SCHEMBL4267384 | 0.81 | BTK (0.52) | BTKMAPTATML3MBTL1TSHR | |
| SCHEMBL161865 | 0.80 | BTK (0.48) | BTKMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL13409319 | 0.78 | BTK (0.50) | BTKMAPTATML3MBTL1TSHR | |
| SCHEMBL13409327 | 0.77 | BTK (0.59) | BTKMAPTATML3MBTL1TSHR | |
| SCHEMBL2228147 | 0.76 | L3MBTL1 (0.36) | BTKMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30803676 | 0.76 | L3MBTL1 (0.36) | BTKMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL13409372 | 0.76 | BTK (0.48) | BTKMAPTATML3MBTL1TSHR | |
| SCHEMBL2667063 | 0.74 | KDM4E (0.45) | MAPTTSHRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL17580818 | 0.74 | BTK (0.50) | BTKMAPTATML3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |