Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409328 | 0.77 | BTK (0.51) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL4267384 | 0.77 | BTK (0.52) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL13409325 | 0.77 | BTK (0.52) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL13409332 | 0.76 | BTK (0.51) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL13409319 | 0.74 | BTK (0.50) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL13409327 | 0.73 | BTK (0.59) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL30744851 | 0.71 | BTK (0.50) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL17580818 | 0.71 | BTK (0.50) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL8143565 | 0.71 | BTK (0.47) | BTKMAPTATMTSHRL3MBTL1 | |
| SCHEMBL13379454 | 0.70 | ALDH1A1 (0.34) | MAPTCYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |