Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409401 | 0.89 | ELANE (0.34) | ELANEALDH1A1TSHRNPSR1 | |
| SCHEMBL8274174 | 0.88 | ALDH1A1 (0.35) | ALDH1A1GAAKDM4ERIPK2TSHR | |
| SCHEMBL8135271 | 0.86 | RIPK2 (0.35) | ALDH1A1GAAKDM4ERIPK2 | |
| SCHEMBL8142266 | 0.85 | RIPK2 (0.34) | ALDH1A1GAAKDM4ERIPK2 | |
| SCHEMBL13409400 | 0.79 | ELANE (0.35) | ELANEALDH1A1KDM4E | |
| SCHEMBL13757313 | 0.71 | CTSG (0.35) | ALDH1A1KDM4E | |
| SCHEMBL13409404 | 0.68 | MAPT (0.35) | ALDH1A1KDM4E | |
| SCHEMBL13409397 | 0.68 | MAPK1 (0.35) | ELANEALDH1A1KDM4E | |
| SCHEMBL13409402 | 0.66 | ADORA2A (0.40) | ELANE | |
| SCHEMBL13409389 | 0.63 | MAPT (0.36) | ELANEALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |