Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 18/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745740 | 0.92 | LMNA (0.41) | CYP3A4LMNAHTTSMN1; SMN2 | |
| SCHEMBL745494 | 0.91 | LMNA (0.43) | CYP3A4LMNAHTTSMN1; SMN2 | |
| SCHEMBL749794 | 0.90 | CYP3A4 (0.40) | CYP3A4 | |
| SCHEMBL746725 | 0.90 | CYP3A4 (0.40) | CYP3A4LMNAHTTSMN1; SMN2 | |
| SCHEMBL747373 | 0.89 | LMNA (0.42) | CYP3A4LMNAHTTSMN1; SMN2 | |
| SCHEMBL764821 | 0.88 | LMNA (0.44) | CYP3A4LMNAHTTSMN1; SMN2 | |
| SCHEMBL749781 | 0.84 | LMNA (0.42) | CYP3A4LMNAHTTSMN1; SMN2 | |
| SCHEMBL12037544 | 0.84 | CYP3A4 (0.43) | CYP3A4 | |
| SCHEMBL12037545 | 0.84 | LMNA (0.43) | CYP3A4LMNAHTTSMN1; SMN2 | |
| SCHEMBL747369 | 0.84 | CLPP (0.45) | CYP3A4LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671054-B1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-02 | — | — | US | disclosed |
| US-7671054-B1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-02 | — | — | US | disclosed |