Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416318 | 0.78 | CYP19A1 (0.48) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL8560818 | 0.77 | CYP19A1 (0.47) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL28265365 | 0.77 | CYP19A1 (0.47) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL28868948 | 0.77 | CYP19A1 (0.47) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL18029763 | 0.77 | CYP19A1 (0.47) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL2360983 | 0.77 | CYP19A1 (0.47) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL16014748 | 0.77 | HDAC1 (0.58) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL28270626 | 0.77 | CYP19A1 (0.47) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL18176973 | 0.73 | CYP19A1 (0.43) | CYP11B1CYP11B2TNFCYP19A1HDAC1 | |
| SCHEMBL1561235 | 0.73 | CYP19A1 (0.43) | CYP11B1CYP11B2TNFCYP19A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |
| US-20100069347-A1 | HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS | MERCK SHARP & DOHME CORP. | 2010-03-18 | — | — | US | disclosed |
| US-20080280836-A1 | Anti-hypercholesterolemic biaryl azetidinone compounds | MORRIELLO GREGORI J | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280836-A1 | Anti-hypercholesterolemic biaryl azetidinone compounds | APOB, PCSK9, CYP46A1 | CYP11B1 165/4885CYP11B2 194/4885TNF 2381/4885 |
| US-20100069347-A1 | HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS | LDLR, PCSK9, CYP46A1 | CYP11B1 65/4885CYP11B2 84/4885TNF 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.