Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416318 | 0.78 | CYP19A1 (0.48) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL13412422 | 0.77 | CYP11B1 (0.49) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL8560818 | 0.77 | CYP19A1 (0.47) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL16014748 | 0.77 | HDAC1 (0.58) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL2360983 | 0.77 | CYP19A1 (0.47) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL18029763 | 0.77 | CYP19A1 (0.47) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL13412425 | 0.73 | CYP19A1 (0.43) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL10570719 | 0.73 | LMNA (0.45) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL20932970 | 0.73 | CYP19A1 (0.43) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 | |
| SCHEMBL1561235 | 0.73 | CYP19A1 (0.43) | CYP19A1HDAC1HDAC6L3MBTL1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053606-A | 4- (4- hydroxy phenyl methylene amino) -1,2,4- triazole -5- thioketones and its application | 湖南大学 | 2018-12-21 | — | — | CN | disclosed |