Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25346624 | 0.79 | USP2 (0.50) | USP2ALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL13414734 | 0.74 | GAA (0.40) | USP2ALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL13449057 | 0.71 | MEN1 (0.31) | MEN1KMT2ACYP2C9 | |
| SCHEMBL12352247 | 0.71 | — | — | |
| SCHEMBL13414730 | 0.69 | GAA (0.37) | USP2ALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL13414706 | 0.68 | KDM4E (0.33) | KDM4E | |
| SCHEMBL26783934 | 0.68 | USP2 (0.60) | USP2ALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL13414642 | 0.68 | GAA (0.33) | ALDH1A1GAAKDM4E | |
| SCHEMBL2984226 | 0.67 | USP2 (0.42) | USP2ALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL13448914 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513417-B2 | Method for synthesis of nitroxyl radical | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | NOX4, TXN2, TXNRD2 | USP2 1595/4885ALDH1A1 130/4885CYP2C19 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.