Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GALK1 | P51570 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19001699 | 0.96 | NPC1 (0.58) | GSTP1MEN1APAF1NPC1LMNA | |
| SCHEMBL15842961 | 0.96 | GSTP1 (0.61) | GSTP1MEN1APAF1NPC1LMNA | |
| SCHEMBL12700857 | 0.94 | GSTP1 (0.59) | GSTP1MEN1APAF1NPC1LMNA | |
| SCHEMBL26503487 | 0.92 | GSTP1 (0.61) | GSTP1MEN1APAF1NPC1LMNA | |
| SCHEMBL23312093 | 0.88 | NPC1 (0.58) | GSTP1MEN1APAF1NPC1LMNA | |
| SCHEMBL2161110 | 0.87 | GSTP1 (0.59) | GSTP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL18545978 | 0.86 | NPC1 (0.66) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL14925857 | 0.81 | GSTP1 (0.53) | GSTP1LMNASMN1; SMN2L3MBTL1CA1 | |
| SCHEMBL2350060 | 0.80 | NPC1 (0.76) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL30481072 | 0.80 | NPC1 (0.76) | MEN1APAF1NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318948-B2 | Fluorene derivatives and organic electronic device using the same | LG CHEM, LTD. (KR) | 2012-11-27 | — | — | US | disclosed |
| US-8318948-B2 | Fluorene derivatives and organic electronic device using the same | LG CHEM, LTD. (KR) | 2012-11-27 | — | — | US | disclosed |
| US-20100071769-A1 | FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2010-03-25 | — | — | US | disclosed |
| US-20100071769-A1 | FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100071769-A1 | FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | VDAC2, VDAC1, FTO | GSTP1 1213/4885MEN1 1788/4885APAF1 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.