Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PI4KA | P42356 | 2/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26152453 | 1.00 | ADA (0.51) | ADAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL24181513 | 1.00 | ADA (0.51) | ADAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL26152478 | 1.00 | ADA (0.51) | ADAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL13415698 | 0.87 | P2RY2 (0.53) | ALDH1A1ADORA1P2RY1P2RY2SRC | |
| SCHEMBL13415639 | 0.86 | NT5E (0.46) | TP53SMN1; SMN2PDE4DPDE3AAHCY | |
| SCHEMBL13415712 | 0.84 | YTHDC1 (0.51) | ADORA2AADORA1P2RY1PDE4DADORA3 | |
| SCHEMBL7162148 | 0.83 | PI4KA (0.57) | ADAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL9548866 | 0.83 | PI4KA (0.57) | ADAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL26152655 | 0.82 | P2RY1 (0.41) | ADAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL24181536 | 0.82 | PI4KA (0.52) | ADAALDH1A1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3936514-B1 | 3'3' CYCLIC DINUCLEOTIDES WITH AN ALKENYLENE | INST OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR V V I (CZ) | 2023-05-24 | — | — | EP | disclosed |
| US-8324179-B2 | Nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20100104532-A1 | NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104532-A1 | NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | SLC29A1, NUDT1, EIF2AK2 | ADA 106/4885ALDH1A1 2008/4885PI4KA 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.