Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788744 | 0.89 | PTGS1 (0.63) | PTGS1PTGS2RAB9AKMT2AMAPT | |
| SCHEMBL11320620 | 0.84 | MAOB (0.50) | RAB9AKMT2ATDP1MEN1NPC1 | |
| SCHEMBL11320604 | 0.84 | MAOB (0.50) | RAB9AKMT2ATDP1MEN1NPC1 | |
| SCHEMBL12307008 | 0.84 | MAPT (0.61) | PTGS1PTGS2RAB9AKMT2AMAPT | |
| SCHEMBL13226178 | 0.84 | MAPT (0.61) | PTGS1PTGS2RAB9AKMT2AMAPT | |
| SCHEMBL12600362 | 0.83 | PTGS1 (0.58) | PTGS1PTGS2RAB9AKMT2AMAPT | |
| SCHEMBL12639953 | 0.83 | PTGS1 (0.58) | PTGS1PTGS2RAB9AKMT2AMAPT | |
| SCHEMBL14433026 | 0.82 | PTGS1 (0.59) | PTGS1PTGS2RAB9AKMT2AMAPT | |
| SCHEMBL18783304 | 0.80 | PTGS1 (0.54) | PTGS1PTGS2RAB9AKMT2AMAPT | |
| SCHEMBL13515171 | 0.79 | KMT2A (0.47) | PTGS1PTGS2RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-20150036204-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS, INC. (CA) | 2015-02-05 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| US-7687598-B2 | Dendrimer and electronic device element employing the same | SHARP KABUSHIKI KAISHA (JP) | 2010-03-30 | — | — | US | disclosed |
| US-7687598-B2 | Dendrimer and electronic device element employing the same | SHARP KABUSHIKI KAISHA (JP) | 2010-03-30 | — | — | US | disclosed |
| US-7585933-B2 | Dendritic polymer and electronic device element employing the polymer | SHARP KABUSHIKI KAISHA (JP) | 2009-09-08 | — | — | US | disclosed |
| US-7531619-B2 | Process for producing dendrimer, building block compound, and process for producing thiophene compound | TOYO GOSEI CO., LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| EP-1535942-B1 | METHOD FOR PRODUCING A ENDRIMER, BUILDING BLOCK COMPOUND, AND METHOD FOR PRODUCING A THIOPHENE COMPOUND | TOYO GOSEI CO LTD (JP) | 2007-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | PTGS1 2576/4885PTGS2 1472/4885RAB9A 937/4885 |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | PTGS1 2576/4885PTGS2 1472/4885RAB9A 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.