Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12639953 | 0.94 | PTGS1 (0.58) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL12600362 | 0.94 | PTGS1 (0.58) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL12307008 | 0.90 | MAPT (0.61) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL13226178 | 0.90 | MAPT (0.61) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL13416012 | 0.89 | PTGS1 (0.58) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL14433026 | 0.87 | PTGS1 (0.59) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL18799227 | 0.87 | RELA (0.53) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL14540196 | 0.87 | RELA (0.58) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL19076185 | 0.87 | RELA (0.58) | PTGS1PTGS2MAPTRAB9ANPC1 | |
| SCHEMBL18783304 | 0.86 | PTGS1 (0.54) | PTGS1PTGS2MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9246103-B2 | Polymers and oligomers with functionalized side groups | MERCK PATENT GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-9200156-B2 | Polymer blends and their use in organic light emitting devices | MERCK PATENT GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-20140175421-A1 | POLYMERS AND OLIGOMERS WITH FUNCTIONALIZED SIDE GROUPS | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-20090184635-A1 | POLYMER BLENDS AND THEIR USE IN ORGANIC LIGHT EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2009-07-23 | — | — | US | disclosed |
| US-20090184635-A1 | POLYMER BLENDS AND THEIR USE IN ORGANIC LIGHT EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2009-07-23 | — | — | US | disclosed |