Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149848 | 0.99 | NPC1 (0.43) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15582449 | 0.99 | NPC1 (0.43) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15397362 | 0.98 | THRB (0.41) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12257778 | 0.98 | THRB (0.43) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14407739 | 0.97 | HTT (0.43) | NPC1LMNACYP3A4THRBMAPT | |
| SCHEMBL15582407 | 0.96 | NPC1 (0.41) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17704624 | 0.95 | HTT (0.41) | NPC1LMNACYP3A4THRBMAPT | |
| SCHEMBL15867565 | 0.95 | NPC1 (0.41) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13109518 | 0.94 | LMNA (0.42) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15582411 | 0.94 | HTT (0.41) | CYP3A4THRBMAPTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671949-B2 | Polarizing plate with optical compensation function, and liquid crystal display device using the same | NITTO DENKO CORPORATION (JP) | 2010-03-02 | — | — | US | disclosed |
| US-7671949-B2 | Polarizing plate with optical compensation function, and liquid crystal display device using the same | NITTO DENKO CORPORATION (JP) | 2010-03-02 | — | — | US | disclosed |