Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968729 | 0.75 | AOC3 (0.64) | AOC3ALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL11620458 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HSD17B10NOS2MAPTKDM4E | |
| SCHEMBL19427449 | 0.71 | DHFR (0.59) | AOC3ALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL1547907 | 0.71 | IDO1 (0.61) | AOC3ALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL19124755 | 0.71 | IDO1 (0.43) | ALDH1A1IDO1HSD17B10MAPTKDM4E | |
| SCHEMBL5252421 | 0.70 | IDO1 (0.66) | AOC3ALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL13168251 | 0.69 | IDO1 (0.54) | AOC3ALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL805159 | 0.69 | HSD17B10 (0.65) | AOC3ALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL20718930 | 0.69 | IDO1 (0.63) | AOC3ALDH1A1IDO1ADRA1ATAAR1 | |
| SCHEMBL5798027 | 0.69 | KDM4E (0.56) | ALDH1A1IDO1ADRA1ATAAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7670847-B2 | Determining enantiomeric excess using indicator-displacement assays | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-03-02 | — | — | US | disclosed |
| US-7332343-B2 | Determining enantiomeric excess using indicator-displacement assays | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-02-19 | — | — | US | disclosed |
| US-20070292968-A1 | Determining Enantiomeric Excess Using Indicator-Displacement Assays | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-12-20 | — | — | US | disclosed |