Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12144250 | 0.81 | HCRTR1 (0.37) | DPP7SLC18A3HTR1A | |
| SCHEMBL23374692 | 0.78 | HTR1A (0.51) | HTR1A | |
| SCHEMBL25044910 | 0.78 | DPP7 (0.42) | DPP7SLC18A3HTR1A | |
| SCHEMBL13228079 | 0.76 | HCRTR1 (0.37) | SLC18A3HTR1A | |
| SCHEMBL23374695 | 0.76 | PIK3CD (0.37) | DPP7HTR1A | |
| SCHEMBL12142250 | 0.76 | GRM2 (0.33) | DPP7HTR1A | |
| SCHEMBL25043641 | 0.73 | DPP7 (0.30) | DPP7 | |
| SCHEMBL12635403 | 0.73 | DPP7 (0.43) | DPP7SLC18A3 | |
| SCHEMBL25125578 | 0.73 | DPP4 (0.31) | DPP7HTR1A | |
| SCHEMBL24575958 | 0.73 | OPRM1 (0.53) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674899-B2 | Dimeric azacyclic compounds and their use | NEUROSEARCH A/S (DK) | 2010-03-09 | — | — | US | disclosed |
| US-20080242668-A1 | Dimeric Azacyclic Compounds and Their Use | NEUROSEARCH A/S (DK) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242668-A1 | Dimeric Azacyclic Compounds and Their Use | CHRNA6, CHRNA5, CHRNA10 | DPP7 1374/4885SLC18A3 360/4885HTR1A 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.