Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 2/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13420642 | 0.86 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AACLYACACA | |
| SCHEMBL13420201 | 0.86 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AACLYACACA | |
| SCHEMBL13420513 | 0.86 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AACLYACACA | |
| SCHEMBL13420433 | 0.86 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AACLYACACA | |
| SCHEMBL14046876 | 0.86 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AACLYACACA | |
| SCHEMBL13644370 | 0.86 | MEN1 (0.49) | HSD11B1MEN1KMT2APRKCGNR1H4 | |
| SCHEMBL29934458 | 0.81 | HSD11B1 (0.49) | HSD11B1MEN1KMT2AACLYACACA | |
| SCHEMBL10049047 | 0.80 | KMT2A (0.67) | HSD11B1MEN1KMT2AACLYACACA | |
| SCHEMBL10350179 | 0.80 | HSD11B1 (0.45) | HSD11B1MEN1KMT2AACLYACACA | |
| SCHEMBL6438953 | 0.79 | MEN1 (0.76) | HSD11B1MEN1KMT2AACLYACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283217-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2012-11-08 | — | — | US | disclosed |
| US-20100056487-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056487-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| WO-2008130449-A2 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283217-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | APP, BACE1, BACE2 | HSD11B1 661/4885MEN1 2197/4885KMT2A 3789/4885 |
| US-20100056487-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | APP, BACE1, BACE2 | HSD11B1 661/4885MEN1 2197/4885KMT2A 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.