Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.54 |
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | ACACA | Q13085 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13420642 | 1.00 | HSD11B1 (0.54) | HSD11B1ACLYACACAPTPN11MEN1 | |
| SCHEMBL13420201 | 1.00 | HSD11B1 (0.54) | HSD11B1ACLYACACAPTPN11MEN1 | |
| SCHEMBL13420433 | 1.00 | HSD11B1 (0.54) | HSD11B1ACLYACACAPTPN11MEN1 | |
| SCHEMBL13420513 | 1.00 | HSD11B1 (0.54) | HSD11B1ACLYACACAPTPN11MEN1 | |
| SCHEMBL13420699 | 0.91 | ACLY (0.54) | HSD11B1ACLYACACAPTPN11MEN1 | |
| SCHEMBL13420519 | 0.91 | ACLY (0.54) | HSD11B1ACLYACACAPTPN11MEN1 | |
| SCHEMBL13420438 | 0.91 | ACLY (0.54) | HSD11B1ACLYACACAPTPN11MEN1 | |
| SCHEMBL13420204 | 0.91 | ACLY (0.54) | HSD11B1ACLYACACAPTPN11MEN1 | |
| SCHEMBL13420517 | 0.90 | ACLY (0.57) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL13420408 | 0.90 | ACLY (0.57) | HSD11B1ACLYACACAPTPN11HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130449-A2 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |