Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCGR3B | O75015 | 1/20 | 0.82 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.82 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.82 |
| ▸ | KCNH3 | Q9ULD8 | 6/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921798 | 0.99 | FCGR3B (0.84) | FCGR3BFCGR1AFCGR2AKCNH3CYP19A1 | |
| SCHEMBL13921837 | 0.95 | FCGR3B (0.78) | FCGR3BFCGR1AFCGR2AKCNH3CYP19A1 | |
| SCHEMBL13421029 | 0.94 | FCGR3B (0.77) | FCGR3BFCGR1AFCGR2AKCNH3CYP19A1 | |
| SCHEMBL13921835 | 0.94 | FCGR3B (0.77) | FCGR3BFCGR1AFCGR2AKCNH3CYP19A1 | |
| SCHEMBL13921795 | 0.94 | FCGR3B (0.77) | FCGR3BFCGR1AFCGR2AKCNH3CYP19A1 | |
| SCHEMBL13921836 | 0.92 | FCGR3B (0.75) | FCGR3BFCGR1AFCGR2AKCNH3CYP19A1 | |
| SCHEMBL13921834 | 0.92 | FCGR3B (0.71) | FCGR3BFCGR1AFCGR2AKCNH3MEN1 | |
| SCHEMBL13921792 | 0.91 | FCGR3B (0.73) | FCGR3BFCGR1AFCGR2AKCNH3CYP19A1 | |
| SCHEMBL13917176 | 0.90 | FCGR3B (1.00) | FCGR3BFCGR1AFCGR2AKCNH3RECQL | |
| SCHEMBL13420995 | 0.90 | FCGR3B (0.79) | FCGR3BFCGR1AFCGR2AKCNH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683061-B2 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC BIOSCIENCES INC. (CA) | 2010-03-23 | — | — | US | disclosed |
| US-7683061-B2 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC BIOSCIENCES INC. (CA) | 2010-03-23 | — | — | US | disclosed |
| US-20090075867-A1 | Triazine compounds and compositions thereof for the treatment of cancers | PROMETIC BIOSCIENCE INC. (CA) | 2009-03-19 | — | — | US | disclosed |
| US-20090075867-A1 | Triazine compounds and compositions thereof for the treatment of cancers | PROMETIC BIOSCIENCE INC. (CA) | 2009-03-19 | — | — | US | disclosed |
| US-20070149528-A1 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC PHARMA SMT LIMITED (GB) | 2007-06-28 | — | — | US | disclosed |
| US-20070149528-A1 | Triazine dimers for the treatment of autoimmune diseases | PROMETIC PHARMA SMT LIMITED (GB) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149528-A1 | Triazine dimers for the treatment of autoimmune diseases | SSB, TLR5, ICOS | FCGR3B 19/4885FCGR1A 18/4885FCGR2A 4/4885 |
| US-20090075867-A1 | Triazine compounds and compositions thereof for the treatment of cancers | MCTS1, TYR, BRAF | FCGR3B 4723/4885FCGR1A 4810/4885FCGR2A 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.